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A clinically useful approach to enhance immunological memory and antitumor immunity
Persistence of vaccine-induced immune responses, not the initial magnitude, best correlates with protective antitumor immunity. In mice, oligonucleotide aptamer-targeted siRNA inhibition of mammalian target of rapamycin (mTOR) activity in activated CD8+ T cells promotes their differentiation into fu...
Autores principales: | Berezhnoy, Alex, Rajagopalan, Anugraha, Gilboa, Eli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091317/ https://www.ncbi.nlm.nih.gov/pubmed/25057446 http://dx.doi.org/10.4161/onci.28811 |
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