Combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer

Immunostimulatory monoclonal antibodies can be given in combinations, hence modulating the activity of 2 or more receptors of the immune system. Some of these combinations have been shown to synergize at the elicitation of therapeutically relevant immune responses in transgenic mice developing spont...

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Autores principales: Morales-Kastresana, Aizea, Labiano, Sara, Gütgemann, Ines, Melero, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091451/
https://www.ncbi.nlm.nih.gov/pubmed/25061546
http://dx.doi.org/10.4161/onci.27812
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author Morales-Kastresana, Aizea
Labiano, Sara
Gütgemann, Ines
Melero, Ignacio
author_facet Morales-Kastresana, Aizea
Labiano, Sara
Gütgemann, Ines
Melero, Ignacio
author_sort Morales-Kastresana, Aizea
collection PubMed
description Immunostimulatory monoclonal antibodies can be given in combinations, hence modulating the activity of 2 or more receptors of the immune system. Some of these combinations have been shown to synergize at the elicitation of therapeutically relevant immune responses in transgenic mice developing spontaneous, oncogene-driven tumors, including multifocal hepatocellular carcinomas expressing ovalbumin as a surrogate tumor-associated antigen.
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spelling pubmed-40914512015-01-16 Combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer Morales-Kastresana, Aizea Labiano, Sara Gütgemann, Ines Melero, Ignacio Oncoimmunology Author's View Immunostimulatory monoclonal antibodies can be given in combinations, hence modulating the activity of 2 or more receptors of the immune system. Some of these combinations have been shown to synergize at the elicitation of therapeutically relevant immune responses in transgenic mice developing spontaneous, oncogene-driven tumors, including multifocal hepatocellular carcinomas expressing ovalbumin as a surrogate tumor-associated antigen. Landes Bioscience 2014-01-16 /pmc/articles/PMC4091451/ /pubmed/25061546 http://dx.doi.org/10.4161/onci.27812 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Morales-Kastresana, Aizea
Labiano, Sara
Gütgemann, Ines
Melero, Ignacio
Combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer
title Combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer
title_full Combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer
title_fullStr Combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer
title_full_unstemmed Combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer
title_short Combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer
title_sort combinations of immunostimulatory antibodies with synergistic effects against spontaneous cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091451/
https://www.ncbi.nlm.nih.gov/pubmed/25061546
http://dx.doi.org/10.4161/onci.27812
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