Cargando…
Functional comparison of single-chain and two-chain anti-CD3-based bispecific antibodies in gene immunotherapy applications
Gene therapy to achieve in vivo secretion of recombinant anti-CD3 x anti-tumor bispecific antibodies in cancer patients is being explored as a strategy to counterbalance rapid renal elimination, thereby sustaining levels of bispecific antibodies in the therapeutic range. Here, we performed a compara...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091452/ https://www.ncbi.nlm.nih.gov/pubmed/25057445 http://dx.doi.org/10.4161/onci.28810 |