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Internal ribosome entry site of bFGF is the target of thalidomide for IMiDs development in multiple myeloma

Although new analogues of immunomodulatory drugs (IMiDs) are being developed for MM, the molecular mechanism of these drugs remains unclear. In the current study, we used MM cell lines as a model to investigate the molecular mechanism of thalidomide and to compare its potency with IMiDs such as poma...

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Detalles Bibliográficos
Autores principales: Lien, I-Chia, Horng, Lin-Yea, Hsu, Pei-Lun, Wu, Chia-Ling, Sung, Hui-Ching, Wu, Rong-Tsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091528/
https://www.ncbi.nlm.nih.gov/pubmed/25053990