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Intracellular lumen extension requires ERM-1-dependent apical membrane expansion and AQP-8-mediated flux
Many unicellular tubes such as capillaries form lumens intracellularly, a process that is not well understood. Here we show that the cortical membrane organizer ERM-1 is required to expand the intracellular apical/lumenal membrane and its actin undercoat during single-cell C.elegans excretory canal...
Autores principales: | Khan, Liakot A., Zhang, Hongjie, Abraham, Nessy, Sun, Lei, Fleming, John T., Buechner, Matthew, Hall, David H., Gobel, Verena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091717/ https://www.ncbi.nlm.nih.gov/pubmed/23334498 http://dx.doi.org/10.1038/ncb2656 |
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