Possible mechanism and clinical potentials of allostery

Allostery is involved in the dynamic regulation of biological functions in proteins. Advances in allostery research have recently drawn great interest and brought allostery closer to the clinic. The present commentary describes the mechanism by which allostery may involve in from a cell-wide view an...

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Detalles Bibliográficos
Autores principales: Huang, Peixin, López Villar, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091739/
https://www.ncbi.nlm.nih.gov/pubmed/25024818
http://dx.doi.org/10.1186/2001-1326-3-18
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author Huang, Peixin
López Villar, Elena
author_facet Huang, Peixin
López Villar, Elena
author_sort Huang, Peixin
collection PubMed
description Allostery is involved in the dynamic regulation of biological functions in proteins. Advances in allostery research have recently drawn great interest and brought allostery closer to the clinic. The present commentary describes the mechanism by which allostery may involve in from a cell-wide view and its contribution to the discovery of new therapeutics to diseases.
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spelling pubmed-40917392014-07-14 Possible mechanism and clinical potentials of allostery Huang, Peixin López Villar, Elena Clin Transl Med Commentary Allostery is involved in the dynamic regulation of biological functions in proteins. Advances in allostery research have recently drawn great interest and brought allostery closer to the clinic. The present commentary describes the mechanism by which allostery may involve in from a cell-wide view and its contribution to the discovery of new therapeutics to diseases. Springer 2014-07-03 /pmc/articles/PMC4091739/ /pubmed/25024818 http://dx.doi.org/10.1186/2001-1326-3-18 Text en Copyright © 2014 Huang and López Villar; licensee Springer. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Commentary
Huang, Peixin
López Villar, Elena
Possible mechanism and clinical potentials of allostery
title Possible mechanism and clinical potentials of allostery
title_full Possible mechanism and clinical potentials of allostery
title_fullStr Possible mechanism and clinical potentials of allostery
title_full_unstemmed Possible mechanism and clinical potentials of allostery
title_short Possible mechanism and clinical potentials of allostery
title_sort possible mechanism and clinical potentials of allostery
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091739/
https://www.ncbi.nlm.nih.gov/pubmed/25024818
http://dx.doi.org/10.1186/2001-1326-3-18
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