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Capping protein is essential for cell migration in vivo and for filopodial morphology and dynamics

Capping protein (CP) binds to barbed ends of growing actin filaments and inhibits elongation. CP is essential for actin-based motility in cell-free systems and in Dictyostelium. Even though CP is believed to be critical for creating the lamellipodial actin structure necessary for protrusion and migr...

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Detalles Bibliográficos
Autores principales: Sinnar, Shamim A., Antoku, Susumu, Saffin, Jean-Michel, Cooper, Jon A., Halpain, Shelley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091828/
https://www.ncbi.nlm.nih.gov/pubmed/24829386
http://dx.doi.org/10.1091/mbc.E13-12-0749

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