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Capping protein is essential for cell migration in vivo and for filopodial morphology and dynamics
Capping protein (CP) binds to barbed ends of growing actin filaments and inhibits elongation. CP is essential for actin-based motility in cell-free systems and in Dictyostelium. Even though CP is believed to be critical for creating the lamellipodial actin structure necessary for protrusion and migr...
Autores principales: | Sinnar, Shamim A., Antoku, Susumu, Saffin, Jean-Michel, Cooper, Jon A., Halpain, Shelley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091828/ https://www.ncbi.nlm.nih.gov/pubmed/24829386 http://dx.doi.org/10.1091/mbc.E13-12-0749 |
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