Gli1 contributes to cellular resistance to cisplatin through altered cellular accumulation of the drug

Cellular resistance to platinum anticancer compounds is governed by no less than two molecular processes; DNA repair and cellular accumulation of drug. Gli1 is an upstream regulator of nucleotide excision repair, effecting this process through c-jun. We, therefore, investigated whether Gli1 plays a...

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Detalles Bibliográficos
Autores principales: AMABLE, LAUREN, FAIN, JASON, GAVIN, ELAINE, REED, EDDIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091882/
https://www.ncbi.nlm.nih.gov/pubmed/24926795
http://dx.doi.org/10.3892/or.2014.3257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091882/
https://www.ncbi.nlm.nih.gov/pubmed/24926795
http://dx.doi.org/10.3892/or.2014.3257

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