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Hypoxia-targeted triple suicide gene therapy radiosensitizes human colorectal cancer cells

The hypoxic microenvironment, an important feature of human solid tumors but absent in normal tissue, may provide an opportunity for cancer-specific gene therapy. The purpose of the present study was to investigate whether hypoxia-driven triple suicide gene TK/CD/UPRT expression enhances cytotoxicit...

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Detalles Bibliográficos
Autores principales:	HSIAO, HUNG TSUNG, XING, LIGANG, DENG, XUELONG, SUN, XIAORONG, LING, C. CLIFTON, LI, GLORIA C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091884/ https://www.ncbi.nlm.nih.gov/pubmed/24912473 http://dx.doi.org/10.3892/or.2014.3238

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