Myeloid-derived suppressor cells link inflammation to cancer

Our recent work has provided the first evidence that MDSCs promote chronic colonic inflammation and colitis-associated carcinogenesis. Our findings not only reveal a novel function of MDSCs in connecting inflammation to cancer, but also provide a rationale for developing effective therapeutic strate...

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Detalles Bibliográficos
Autores principales: Wang, Dingzhi, DuBois, Raymond N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092003/
https://www.ncbi.nlm.nih.gov/pubmed/25054088
http://dx.doi.org/10.4161/onci.28581
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author Wang, Dingzhi
DuBois, Raymond N
author_facet Wang, Dingzhi
DuBois, Raymond N
author_sort Wang, Dingzhi
collection PubMed
description Our recent work has provided the first evidence that MDSCs promote chronic colonic inflammation and colitis-associated carcinogenesis. Our findings not only reveal a novel function of MDSCs in connecting inflammation to cancer, but also provide a rationale for developing effective therapeutic strategies to subvert inflammation- and tumor-induced immunosuppression.
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spelling pubmed-40920032014-07-22 Myeloid-derived suppressor cells link inflammation to cancer Wang, Dingzhi DuBois, Raymond N Oncoimmunology Author's View Our recent work has provided the first evidence that MDSCs promote chronic colonic inflammation and colitis-associated carcinogenesis. Our findings not only reveal a novel function of MDSCs in connecting inflammation to cancer, but also provide a rationale for developing effective therapeutic strategies to subvert inflammation- and tumor-induced immunosuppression. Landes Bioscience 2014-04-29 /pmc/articles/PMC4092003/ /pubmed/25054088 http://dx.doi.org/10.4161/onci.28581 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Wang, Dingzhi
DuBois, Raymond N
Myeloid-derived suppressor cells link inflammation to cancer
title Myeloid-derived suppressor cells link inflammation to cancer
title_full Myeloid-derived suppressor cells link inflammation to cancer
title_fullStr Myeloid-derived suppressor cells link inflammation to cancer
title_full_unstemmed Myeloid-derived suppressor cells link inflammation to cancer
title_short Myeloid-derived suppressor cells link inflammation to cancer
title_sort myeloid-derived suppressor cells link inflammation to cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092003/
https://www.ncbi.nlm.nih.gov/pubmed/25054088
http://dx.doi.org/10.4161/onci.28581
work_keys_str_mv AT wangdingzhi myeloidderivedsuppressorcellslinkinflammationtocancer
AT duboisraymondn myeloidderivedsuppressorcellslinkinflammationtocancer

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