Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy

IL-9-producing cytotoxic T (Tc9) cells represent a unique CD8(+) T-cell subset. These long-lived immune cells possess the capacity to acquire effector function and home to tumor tissues after adoptive transfer. IL-9 is indispensable for Tc9-mediated superior antitumor response. These findings are hi...

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Detalles Bibliográficos
Autores principales: Lu, Yong, Wang, Qiang, Yi, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092006/
https://www.ncbi.nlm.nih.gov/pubmed/25054087
http://dx.doi.org/10.4161/onci.28542
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author Lu, Yong
Wang, Qiang
Yi, Qing
author_facet Lu, Yong
Wang, Qiang
Yi, Qing
author_sort Lu, Yong
collection PubMed
description IL-9-producing cytotoxic T (Tc9) cells represent a unique CD8(+) T-cell subset. These long-lived immune cells possess the capacity to acquire effector function and home to tumor tissues after adoptive transfer. IL-9 is indispensable for Tc9-mediated superior antitumor response. These findings are highly significant and crucial to achieve advances in T cell-based adoptive therapies.
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spelling pubmed-40920062014-07-22 Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy Lu, Yong Wang, Qiang Yi, Qing Oncoimmunology Author's View IL-9-producing cytotoxic T (Tc9) cells represent a unique CD8(+) T-cell subset. These long-lived immune cells possess the capacity to acquire effector function and home to tumor tissues after adoptive transfer. IL-9 is indispensable for Tc9-mediated superior antitumor response. These findings are highly significant and crucial to achieve advances in T cell-based adoptive therapies. Landes Bioscience 2014-04-29 /pmc/articles/PMC4092006/ /pubmed/25054087 http://dx.doi.org/10.4161/onci.28542 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Lu, Yong
Wang, Qiang
Yi, Qing
Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy
title Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy
title_full Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy
title_fullStr Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy
title_full_unstemmed Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy
title_short Anticancer Tc9 cells: Long-lived tumor-killing T cells for adoptive therapy
title_sort anticancer tc9 cells: long-lived tumor-killing t cells for adoptive therapy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092006/
https://www.ncbi.nlm.nih.gov/pubmed/25054087
http://dx.doi.org/10.4161/onci.28542
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AT wangqiang anticancertc9cellslonglivedtumorkillingtcellsforadoptivetherapy
AT yiqing anticancertc9cellslonglivedtumorkillingtcellsforadoptivetherapy

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