Reproductive Senescence Blunts Response of Estrogen Receptor-α Expression to Estrogen Treatment in Rat Post-Ischemic Cerebral Microvessels

BACKGROUND: Several studies demonstrate that estrogen treatment improves cerebral blood flow in ischemic brain regions of young ovariectomized (OVX) rats. Estrogen receptor-α (ER-α) may mediate estrogen’s beneficial actions via its effects on the cerebral microvasculature. However, estrogen-derived...

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Detalles Bibliográficos
Autores principales: Zeynalov, Emil, Rezvani, Niloofar, Miyazaki, Chikao, Liu, Xiaoguang, Littleton-Kearney, Marguerite T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092076/
https://www.ncbi.nlm.nih.gov/pubmed/25010766
http://dx.doi.org/10.1371/journal.pone.0102194

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