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Fumaric Acid Esters Can Block Pro-Inflammatory Actions of Human CRP and Ameliorate Metabolic Disturbances in Transgenic Spontaneously Hypertensive Rats

Inflammation and oxidative stress have been implicated in the pathogenesis of metabolic disturbances. Esters of fumaric acid, mainly dimethyl fumarate, exhibit immunomodulatory, anti-inflammatory, and anti-oxidative effects. In the current study, we tested the hypothesis that fumaric acid ester (FAE...

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Detalles Bibliográficos
Autores principales:	Šilhavý, Jan, Zídek, Václav, Mlejnek, Petr, Landa, Vladimír, Šimáková, Miroslava, Strnad, Hynek, Oliyarnyk, Olena, Škop, Vojtěch, Kazdová, Ludmila, Kurtz, Theodore, Pravenec, Michal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092096/ https://www.ncbi.nlm.nih.gov/pubmed/25010431 http://dx.doi.org/10.1371/journal.pone.0101906

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