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The Impact of Simvastatin on Pulmonary Effectors of Pseudomonas aeruginosa Infection
The statin family of cholesterol-lowering drugs is known to have pleiotropic properties which include anti-inflammatory and immunomodulatory effects. Statins exert their pleiotropic effects by altering expression of human immune regulators including pro-inflammatory cytokines. Previously we found th...
Autores principales: | Hennessy, Emma, O'Callaghan, Julie, Mooij, Marlies J., Legendre, Claire, Camacho-Vanegas, Olga, Camacho, Sandra C., Adams, Claire, Martignetti, John A., O'Gara, Fergal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092124/ https://www.ncbi.nlm.nih.gov/pubmed/25010049 http://dx.doi.org/10.1371/journal.pone.0102200 |
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