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Sphingosine Kinase-2 Maintains Viral Latency and Survival for KSHV-Infected Endothelial Cells

Phosphorylation of sphingosine by sphingosine kinases (SphK1 and SphK2) generates sphingosine-1-phosphate (S1P), a bioactive sphingolipid which promotes cancer cell survival and tumor progression in vivo. We have recently reported that targeting SphK2 induces apoptosis for human primary effusion lym...

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Detalles Bibliográficos
Autores principales:	Dai, Lu, Plaisance-Bonstaff, Karlie, Voelkel-Johnson, Christina, Smith, Charles D., Ogretmen, Besim, Qin, Zhiqiang, Parsons, Chris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092155/ https://www.ncbi.nlm.nih.gov/pubmed/25010828 http://dx.doi.org/10.1371/journal.pone.0102314

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