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Enrichment of MTHFR 677 T in a Chinese long-lived cohort and its association with lipid modulation

BACKGROUND: Variants in the Methylenetetrahydrofolate reductase (MTHFR) gene may result in a lowered catalytic activity and associate with subsequent elevated serum homocysteine (Hcy) concentration, abnormal DNA synthesis and methylation, cardiovascular risk, and unhealthy aging. Several investigati...

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Detalles Bibliográficos
Autores principales: Chen, Ning-Yuan, Liu, Cheng-Wu, Du, Li-Li, Xiao, Li-Ping, Ge, Lin, Wang, Yi-Yuan, Wei, Zhen, Wu, Hua-Yu, Luo, Chen-Yuan, Liang, Liang, Peng, Jun-Hua, Luo, Xiao-Qiu, Yin, Rui-Xing, Nguyen, Cuc Phuong, Pan, Shang-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092207/
https://www.ncbi.nlm.nih.gov/pubmed/24968810
http://dx.doi.org/10.1186/1476-511X-13-104