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Bioinformatic analysis of ciliary transition zone proteins reveals insights into the evolution of ciliopathy networks

BACKGROUND: Cilia are critical for diverse functions, from motility to signal transduction, and ciliary dysfunction causes inherited diseases termed ciliopathies. Several ciliopathy proteins influence developmental signalling and aberrant signalling explains many ciliopathy phenotypes. Ciliary compa...

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Detalles Bibliográficos
Autores principales: Barker, Amy R, Renzaglia, Karen S, Fry, Kimberley, Dawe, Helen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092220/
https://www.ncbi.nlm.nih.gov/pubmed/24969356
http://dx.doi.org/10.1186/1471-2164-15-531