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D-K(6)L(9) Peptide Combination with IL-12 Inhibits the Recurrence of Tumors in Mice

D-K(6)L(9) peptide is bound by phosphatidylserine and induces necrosis in cancer cells. In our therapeutic experience, this peptide, when administered directly into B16-F10 murine melanoma tumors, inhibited their growth. Cessation of therapy results, however, in tumor relapse. We aimed at developing...

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Detalles Bibliográficos
Autores principales: Cichoń, Tomasz, Smolarczyk, Ryszard, Matuszczak, Sybilla, Barczyk, Magdalena, Jarosz, Magdalena, Szala, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Basel 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092230/
https://www.ncbi.nlm.nih.gov/pubmed/24487722
http://dx.doi.org/10.1007/s00005-014-0268-z