Tuning Pharmacokinetics and Biodistribution of a Targeted Drug Delivery System Through Incorporation of a Passive Targeting Component

Major challenges in the development of drug delivery systems (DDSs) have been the short half-life, poor bioavailability, insufficient accumulation and penetration of the DDSs into the tumor tissue. Understanding the pharmacokinetic (PK) parameters of the DDS is essential to overcome these challenges...

Descripción completa

Detalles Bibliográficos
Autores principales: Kudgus, Rachel A., Walden, Chad A., McGovern, Renee M., Reid, Joel M., Robertson, J. David, Mukherjee, Priyabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092331/
https://www.ncbi.nlm.nih.gov/pubmed/25011609
http://dx.doi.org/10.1038/srep05669

Ejemplares similares

Ejemplares similares