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The Signaling Mechanism of TGF-β(1) Induced Bovine Mammary Epithelial Cell Apoptosis

The present study showed that Transforming growth factor beta 1 (TGF-β(1)) can induce apoptosis of bovine mammary epithelial cells. This apoptosis was also observed with phosphorylation of Smad2/3 within 0.5–2 h. Afterwards the signal transferred into the nucleus. Moreover, intracellular free Ca(2+)...

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Detalles Bibliográficos
Autores principales: Di, He-Shuang, Wang, Li-Gang, Wang, Gen-Lin, Zhou, Lei, Yang, Yuan-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092962/
https://www.ncbi.nlm.nih.gov/pubmed/25049567
http://dx.doi.org/10.5713/ajas.2011.11251