A polymer-based ratiometric intracellular glucose sensor

The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of...

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Detalles Bibliográficos
Autores principales: Zhang, Liqiang, Su, Fengyu, Buizer, Sean, Kong, Xiangxing, Lee, Fred, Day, Kevin, Tian, Yanqing, Meldrum, Deirdre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093769/
https://www.ncbi.nlm.nih.gov/pubmed/24840577
http://dx.doi.org/10.1039/c4cc01110d
Descripción
Sumario:The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of the polymer within HeLa cells were investigated.

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