Cargando…

A polymer-based ratiometric intracellular glucose sensor

The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Liqiang, Su, Fengyu, Buizer, Sean, Kong, Xiangxing, Lee, Fred, Day, Kevin, Tian, Yanqing, Meldrum, Deirdre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093769/
https://www.ncbi.nlm.nih.gov/pubmed/24840577
http://dx.doi.org/10.1039/c4cc01110d
_version_ 1782325773390053376
author Zhang, Liqiang
Su, Fengyu
Buizer, Sean
Kong, Xiangxing
Lee, Fred
Day, Kevin
Tian, Yanqing
Meldrum, Deirdre R.
author_facet Zhang, Liqiang
Su, Fengyu
Buizer, Sean
Kong, Xiangxing
Lee, Fred
Day, Kevin
Tian, Yanqing
Meldrum, Deirdre R.
author_sort Zhang, Liqiang
collection PubMed
description The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of the polymer within HeLa cells were investigated.
format Online
Article
Text
id pubmed-4093769
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-40937692014-07-16 A polymer-based ratiometric intracellular glucose sensor Zhang, Liqiang Su, Fengyu Buizer, Sean Kong, Xiangxing Lee, Fred Day, Kevin Tian, Yanqing Meldrum, Deirdre R. Chem Commun (Camb) Chemistry The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide) (PHPMA) and poly[2-(methacryloyloxy)ethyl]trimethylammonium chloride (PMAETMA) was synthesized. Cellular internalization and glucose response of the polymer within HeLa cells were investigated. Royal Society of Chemistry 2014-07-04 2014-05-19 /pmc/articles/PMC4093769/ /pubmed/24840577 http://dx.doi.org/10.1039/c4cc01110d Text en This journal is © The Royal Society of Chemistry 2014 http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Zhang, Liqiang
Su, Fengyu
Buizer, Sean
Kong, Xiangxing
Lee, Fred
Day, Kevin
Tian, Yanqing
Meldrum, Deirdre R.
A polymer-based ratiometric intracellular glucose sensor
title A polymer-based ratiometric intracellular glucose sensor
title_full A polymer-based ratiometric intracellular glucose sensor
title_fullStr A polymer-based ratiometric intracellular glucose sensor
title_full_unstemmed A polymer-based ratiometric intracellular glucose sensor
title_short A polymer-based ratiometric intracellular glucose sensor
title_sort polymer-based ratiometric intracellular glucose sensor
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093769/
https://www.ncbi.nlm.nih.gov/pubmed/24840577
http://dx.doi.org/10.1039/c4cc01110d
work_keys_str_mv AT zhangliqiang apolymerbasedratiometricintracellularglucosesensor
AT sufengyu apolymerbasedratiometricintracellularglucosesensor
AT buizersean apolymerbasedratiometricintracellularglucosesensor
AT kongxiangxing apolymerbasedratiometricintracellularglucosesensor
AT leefred apolymerbasedratiometricintracellularglucosesensor
AT daykevin apolymerbasedratiometricintracellularglucosesensor
AT tianyanqing apolymerbasedratiometricintracellularglucosesensor
AT meldrumdeirdrer apolymerbasedratiometricintracellularglucosesensor
AT zhangliqiang polymerbasedratiometricintracellularglucosesensor
AT sufengyu polymerbasedratiometricintracellularglucosesensor
AT buizersean polymerbasedratiometricintracellularglucosesensor
AT kongxiangxing polymerbasedratiometricintracellularglucosesensor
AT leefred polymerbasedratiometricintracellularglucosesensor
AT daykevin polymerbasedratiometricintracellularglucosesensor
AT tianyanqing polymerbasedratiometricintracellularglucosesensor
AT meldrumdeirdrer polymerbasedratiometricintracellularglucosesensor