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Spliceozymes: Ribozymes that Remove Introns from Pre-mRNAs in Trans
Group I introns are pre-mRNA introns that do not require the spliceosome for their removal. Instead, they fold into complex three-dimensional structures and catalyze two transesterification reactions, thereby excising themselves and joining the flanking exons. These catalytic RNAs (ribozymes) have b...
Autores principales: | Amini, Zhaleh N., Olson, Karen E., Müller, Ulrich F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094466/ https://www.ncbi.nlm.nih.gov/pubmed/25014025 http://dx.doi.org/10.1371/journal.pone.0101932 |
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