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Validation of a LC-MS/MS Method for Quantifying Urinary Nicotine, Six Nicotine Metabolites and the Minor Tobacco Alkaloids—Anatabine and Anabasine—in Smokers' Urine
Tobacco use is a major contributor to premature morbidity and mortality. The measurement of nicotine and its metabolites in urine is a valuable tool for evaluating nicotine exposure and for nicotine metabolic profiling—i.e., metabolite ratios. In addition, the minor tobacco alkaloids—anabasine and a...
Autores principales: | McGuffey, James E., Wei, Binnian, Bernert, John T., Morrow, John C., Xia, Baoyun, Wang, Lanqing, Blount, Benjamin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094486/ https://www.ncbi.nlm.nih.gov/pubmed/25013964 http://dx.doi.org/10.1371/journal.pone.0101816 |
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