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Disruption of Ion-Trafficking System in the Cochlear Spiral Ligament Prior to Permanent Hearing Loss Induced by Exposure to Intense Noise: Possible Involvement of 4-Hydroxy-2-Nonenal as a Mediator of Oxidative Stress

Noise-induced hearing loss is at least in part due to disruption of endocochlear potential, which is maintained by various K(+) transport apparatuses including Na(+), K(+)-ATPase and gap junction-mediated intercellular communication in the lateral wall structures. In this study, we examined the chan...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Taro, Nagashima, Reiko, Yoneyama, Masanori, Shiba, Tatsuo, Ogita, Kiyokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094500/
https://www.ncbi.nlm.nih.gov/pubmed/25013956
http://dx.doi.org/10.1371/journal.pone.0102133