mTOR Inhibition by Everolimus in Childhood Acute Lymphoblastic Leukemia Induces Caspase-Independent Cell Death

Increasingly, anti-cancer medications are being reported to induce cell death mechanisms other than apoptosis. Activating alternate death mechanisms introduces the potential to kill cells that have defects in their apoptotic machinery, as is commonly observed in cancer cells, including in hematologi...

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Detalles Bibliográficos
Autores principales: Baraz, Rana, Cisterne, Adam, Saunders, Philip O., Hewson, John, Thien, Marilyn, Weiss, Jocelyn, Basnett, Jordan, Bradstock, Kenneth F., Bendall, Linda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094511/
https://www.ncbi.nlm.nih.gov/pubmed/25014496
http://dx.doi.org/10.1371/journal.pone.0102494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094511/
https://www.ncbi.nlm.nih.gov/pubmed/25014496
http://dx.doi.org/10.1371/journal.pone.0102494

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