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mTOR Inhibition by Everolimus in Childhood Acute Lymphoblastic Leukemia Induces Caspase-Independent Cell Death
Increasingly, anti-cancer medications are being reported to induce cell death mechanisms other than apoptosis. Activating alternate death mechanisms introduces the potential to kill cells that have defects in their apoptotic machinery, as is commonly observed in cancer cells, including in hematologi...
Autores principales: | Baraz, Rana, Cisterne, Adam, Saunders, Philip O., Hewson, John, Thien, Marilyn, Weiss, Jocelyn, Basnett, Jordan, Bradstock, Kenneth F., Bendall, Linda J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094511/ https://www.ncbi.nlm.nih.gov/pubmed/25014496 http://dx.doi.org/10.1371/journal.pone.0102494 |
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