Assessing Accuracy of Genotype Imputation in American Indians

BACKGROUND: Genotype imputation is commonly used in genetic association studies to test untyped variants using information on linkage disequilibrium (LD) with typed markers. Imputing genotypes requires a suitable reference population in which the LD pattern is known, most often one selected from Hap...

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Detalles Bibliográficos
Autores principales: Malhotra, Alka, Kobes, Sayuko, Bogardus, Clifton, Knowler, William C., Baier, Leslie J., Hanson, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094523/
https://www.ncbi.nlm.nih.gov/pubmed/25014012
http://dx.doi.org/10.1371/journal.pone.0102544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094523/
https://www.ncbi.nlm.nih.gov/pubmed/25014012
http://dx.doi.org/10.1371/journal.pone.0102544

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