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Assessing Accuracy of Genotype Imputation in American Indians
BACKGROUND: Genotype imputation is commonly used in genetic association studies to test untyped variants using information on linkage disequilibrium (LD) with typed markers. Imputing genotypes requires a suitable reference population in which the LD pattern is known, most often one selected from Hap...
Autores principales: | Malhotra, Alka, Kobes, Sayuko, Bogardus, Clifton, Knowler, William C., Baier, Leslie J., Hanson, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094523/ https://www.ncbi.nlm.nih.gov/pubmed/25014012 http://dx.doi.org/10.1371/journal.pone.0102544 |
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