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PARP-Inhibitor Treatment Prevents Hypertension Induced Cardiac Remodeling by Favorable Modulation of Heat Shock Proteins, Akt-1/GSK-3β and Several PKC Isoforms

Spontaneously hypertensive rat (SHR) is a suitable model for studies of the complications of hypertension. It is known that activation of poly(ADP-ribose) polymerase enzyme (PARP) plays an important role in the development of postinfarction as well as long-term hypertension induced heart failure. In...

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Detalles Bibliográficos
Autores principales:	Deres, Laszlo, Bartha, Eva, Palfi, Anita, Eros, Krisztian, Riba, Adam, Lantos, Janos, Kalai, Tamas, Hideg, Kalman, Sumegi, Balazs, Gallyas, Ferenc, Toth, Kalman, Halmosi, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094529/ https://www.ncbi.nlm.nih.gov/pubmed/25014216 http://dx.doi.org/10.1371/journal.pone.0102148

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