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Liposome Reconstitution and Modulation of Recombinant Prenylated Human Rac1 by GEFs, GDI1 and Pak1

Small Rho GTPases are well known to regulate a variety of cellular processes by acting as molecular switches. The regulatory function of Rho GTPases is critically dependent on their posttranslational modification at the carboxyl terminus by isoprenylation and association with proper cellular membran...

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Detalles Bibliográficos
Autores principales: Zhang, Si-Cai, Gremer, Lothar, Heise, Henrike, Janning, Petra, Shymanets, Aliaksei, Cirstea, Ion C., Krause, Eberhard, Nürnberg, Bernd, Ahmadian, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094549/
https://www.ncbi.nlm.nih.gov/pubmed/25014207
http://dx.doi.org/10.1371/journal.pone.0102425