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Design of oral agents for the management of multiple sclerosis: benefit and risk assessment for dimethyl fumarate
Dimethyl fumarate (DMF) is the most recent oral disease-modifying therapy approved by the US Food and Drug Administration and is indicated for the treatment of relapsing forms of multiple sclerosis (MS). Prior to approval for use in MS, DMF and its active metabolite, monomethyl fumarate, had been us...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094574/ https://www.ncbi.nlm.nih.gov/pubmed/25045248 http://dx.doi.org/10.2147/DDDT.S50962 |