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Therapeutic suppression of premature termination codons: Mechanisms and clinical considerations (Review)
An estimated one-third of genetic disorders are the result of mutations that generate premature termination codons (PTCs) within protein coding genes. These disorders are phenotypically diverse and consist of diseases that affect both young and old individuals. Various small molecules have been iden...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094583/ https://www.ncbi.nlm.nih.gov/pubmed/24939317 http://dx.doi.org/10.3892/ijmm.2014.1809 |