Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids

Antiglomerular basement membrane disease presenting during pregnancy is very uncommon. We present a case of a pregnant female who presented with acute renal failure needing dialysis from Goodpasture's disease. She responded very well to just plasma exchange, high dose steroids, and hemodialysis...

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Autores principales: Muqeet Adnan, Mohammed, Morton, Jordan, Hashmi, Syed, Abdul Mujeeb, Sufyan, Kern, William, Cowley, Benjamin Jr.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094861/
https://www.ncbi.nlm.nih.gov/pubmed/25050187
http://dx.doi.org/10.1155/2014/243746
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author Muqeet Adnan, Mohammed
Morton, Jordan
Hashmi, Syed
Abdul Mujeeb, Sufyan
Kern, William
Cowley, Benjamin Jr.
author_facet Muqeet Adnan, Mohammed
Morton, Jordan
Hashmi, Syed
Abdul Mujeeb, Sufyan
Kern, William
Cowley, Benjamin Jr.
author_sort Muqeet Adnan, Mohammed
collection PubMed
description Antiglomerular basement membrane disease presenting during pregnancy is very uncommon. We present a case of a pregnant female who presented with acute renal failure needing dialysis from Goodpasture's disease. She responded very well to just plasma exchange, high dose steroids, and hemodialysis. Cyclophosphamide was never started on this patient. She had a spontaneous abortion in her 8th week of pregnancy and henceforth did very well to regain her renal function. Patient became hemodialysis independent at 2 months and returned to her baseline kidney function at 6 months. We present this remarkable case of recovery from acute renal failure in a patient with anti-GBM disease. We think the flare-up of renal failure was pregnancy related which resolved after spontaneous abortion.
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spelling pubmed-40948612014-07-21 Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids Muqeet Adnan, Mohammed Morton, Jordan Hashmi, Syed Abdul Mujeeb, Sufyan Kern, William Cowley, Benjamin Jr. Case Rep Nephrol Case Report Antiglomerular basement membrane disease presenting during pregnancy is very uncommon. We present a case of a pregnant female who presented with acute renal failure needing dialysis from Goodpasture's disease. She responded very well to just plasma exchange, high dose steroids, and hemodialysis. Cyclophosphamide was never started on this patient. She had a spontaneous abortion in her 8th week of pregnancy and henceforth did very well to regain her renal function. Patient became hemodialysis independent at 2 months and returned to her baseline kidney function at 6 months. We present this remarkable case of recovery from acute renal failure in a patient with anti-GBM disease. We think the flare-up of renal failure was pregnancy related which resolved after spontaneous abortion. Hindawi Publishing Corporation 2014 2014-06-24 /pmc/articles/PMC4094861/ /pubmed/25050187 http://dx.doi.org/10.1155/2014/243746 Text en Copyright © 2014 Mohammed Muqeet Adnan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Muqeet Adnan, Mohammed
Morton, Jordan
Hashmi, Syed
Abdul Mujeeb, Sufyan
Kern, William
Cowley, Benjamin Jr.
Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_full Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_fullStr Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_full_unstemmed Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_short Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids
title_sort anti-gbm of pregnancy: acute renal failure resolved after spontaneous abortion, plasma exchange, hemodialysis, and steroids
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094861/
https://www.ncbi.nlm.nih.gov/pubmed/25050187
http://dx.doi.org/10.1155/2014/243746
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