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Genome-Wide Analysis of Alpharetroviral Integration in Human Hematopoietic Stem/Progenitor Cells
Gene transfer vectors derived from gamma-retroviruses or lentiviruses are currently used for the gene therapy of genetic or acquired diseases. Retroviral vectors display a non-random integration pattern in the human genome, targeting either regulatory regions (gamma-retroviruses) or the transcribed...
Autores principales: | Moiani, Arianna, Suerth, Julia Debora, Gandolfi, Francesco, Rizzi, Ermanno, Severgnini, Marco, De Bellis, Gianluca, Schambach, Axel, Mavilio, Fulvio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094940/ https://www.ncbi.nlm.nih.gov/pubmed/24840152 http://dx.doi.org/10.3390/genes5020415 |
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