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Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage
BACKGROUND: Immune recognition of foreign proteins by T cells hinges on the formation of a ternary complex sandwiching a constituent peptide of the protein between a major histocompatibility complex (MHC) molecule and a T cell receptor (TCR). Viruses have evolved means of "camouflaging" th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094998/ https://www.ncbi.nlm.nih.gov/pubmed/25104221 http://dx.doi.org/10.1186/1471-2105-15-S4-S1 |