Cargando…

Integrated assessment of predicted MHC binding and cross-conservation with self reveals patterns of viral camouflage

BACKGROUND: Immune recognition of foreign proteins by T cells hinges on the formation of a ternary complex sandwiching a constituent peptide of the protein between a major histocompatibility complex (MHC) molecule and a T cell receptor (TCR). Viruses have evolved means of "camouflaging" th...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Lu, De Groot, Anne S, Gutierrez, Andres H, Martin, William D, Moise, Lenny, Bailey-Kellogg, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094998/
https://www.ncbi.nlm.nih.gov/pubmed/25104221
http://dx.doi.org/10.1186/1471-2105-15-S4-S1