High level expression of a glutamate-gated chloride channel gene in reproductive tissues of Brugia malayi may explain the sterilizing effect of ivermectin on filarial worms()

Glutamate-gated chloride channels (GluCl) are targets for avermectin/milbemycin (A/M) anthelmintics such as ivermectin that cause paralysis of somatic and pharyngeal muscles in gastrointestinal nematodes. Ivermectin is useful for onchocerciasis control programs because of its activity against microf...

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Detalles Bibliográficos
Autores principales: Li, Ben Wen, Rush, Amy C., Weil, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095040/
https://www.ncbi.nlm.nih.gov/pubmed/25057456
http://dx.doi.org/10.1016/j.ijpddr.2014.01.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095040/
https://www.ncbi.nlm.nih.gov/pubmed/25057456
http://dx.doi.org/10.1016/j.ijpddr.2014.01.002

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