An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer

INTRODUCTION: Transforming growth factor-βs (TGF-βs) play a dual role in breast cancer, with context-dependent tumor-suppressive or pro-oncogenic effects. TGF-β antagonists are showing promise in early-phase clinical oncology trials to neutralize the pro-oncogenic effects. However, there is currentl...

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Detalles Bibliográficos
Autores principales: Sato, Misako, Kadota, Mitsutaka, Tang, Binwu, Yang, Howard H, Yang, Yu-an, Shan, Mengge, Weng, Jia, Welsh, Michael A, Flanders, Kathleen C, Nagano, Yoshiko, Michalowski, Aleksandra M, Clifford, Robert J, Lee, Maxwell P, Wakefield, Lalage M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095608/
https://www.ncbi.nlm.nih.gov/pubmed/24890385
http://dx.doi.org/10.1186/bcr3668

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