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Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole?

Since its introduction to the intensive care setting a decade ago, B-type natriuretic peptide has been the focus of studies in different areas (in particular, sepsis). With this biomarker, as with many newly identified biomarkers, its diagnostic performance was pursued initially and then its ability...

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Detalles Bibliográficos
Autores principales: McLean, Anthony S, Huang, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095610/
https://www.ncbi.nlm.nih.gov/pubmed/25042534
http://dx.doi.org/10.1186/cc13960
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author McLean, Anthony S
Huang, Stephen J
author_facet McLean, Anthony S
Huang, Stephen J
author_sort McLean, Anthony S
collection PubMed
description Since its introduction to the intensive care setting a decade ago, B-type natriuretic peptide has been the focus of studies in different areas (in particular, sepsis). With this biomarker, as with many newly identified biomarkers, its diagnostic performance was pursued initially and then its ability to predict outcomes. Despite all the efforts, results have not been consistent and the applications of B-type natriuretic peptide in the intensive care setting remain by and large academic. Will such studies one day become clinical practice? Or are we too obsessed with finding a place for every biomarker?
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spelling pubmed-40956102015-07-01 Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole? McLean, Anthony S Huang, Stephen J Crit Care Commentary Since its introduction to the intensive care setting a decade ago, B-type natriuretic peptide has been the focus of studies in different areas (in particular, sepsis). With this biomarker, as with many newly identified biomarkers, its diagnostic performance was pursued initially and then its ability to predict outcomes. Despite all the efforts, results have not been consistent and the applications of B-type natriuretic peptide in the intensive care setting remain by and large academic. Will such studies one day become clinical practice? Or are we too obsessed with finding a place for every biomarker? BioMed Central 2014 2014-07-01 /pmc/articles/PMC4095610/ /pubmed/25042534 http://dx.doi.org/10.1186/cc13960 Text en Copyright © 2014 McLean and Huang; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
McLean, Anthony S
Huang, Stephen J
Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole?
title Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole?
title_full Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole?
title_fullStr Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole?
title_full_unstemmed Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole?
title_short Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole?
title_sort brain not processing: is finding a role for bnp in sepsis like fitting a square peg into a round hole?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095610/
https://www.ncbi.nlm.nih.gov/pubmed/25042534
http://dx.doi.org/10.1186/cc13960
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