Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary

The role of infection in the etiology of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is poorly understood. Large-scale epidemiological descriptions of the histology and microbiology of BRONJ are not found in the literature. Herein, we present a systematic review of BRONJ histology and mi...

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Detalles Bibliográficos
Autores principales: Hinson, A. M., Smith, C. W., Siegel, E. R., Stack, B. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095654/
https://www.ncbi.nlm.nih.gov/pubmed/25089126
http://dx.doi.org/10.1155/2014/452737
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author Hinson, A. M.
Smith, C. W.
Siegel, E. R.
Stack, B. C.
author_facet Hinson, A. M.
Smith, C. W.
Siegel, E. R.
Stack, B. C.
author_sort Hinson, A. M.
collection PubMed
description The role of infection in the etiology of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is poorly understood. Large-scale epidemiological descriptions of the histology and microbiology of BRONJ are not found in the literature. Herein, we present a systematic review of BRONJ histology and microbiology (including demographics, immunocompromised associations, clinical signs and symptoms, disease severity, antibiotic and surgical treatments, and recovery status) validating that infection should still be considered a prime component in the multifactorial disease.
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spelling pubmed-40956542014-08-03 Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary Hinson, A. M. Smith, C. W. Siegel, E. R. Stack, B. C. Int J Dent Review Article The role of infection in the etiology of bisphosphonate-related osteonecrosis of the jaw (BRONJ) is poorly understood. Large-scale epidemiological descriptions of the histology and microbiology of BRONJ are not found in the literature. Herein, we present a systematic review of BRONJ histology and microbiology (including demographics, immunocompromised associations, clinical signs and symptoms, disease severity, antibiotic and surgical treatments, and recovery status) validating that infection should still be considered a prime component in the multifactorial disease. Hindawi Publishing Corporation 2014 2014-06-24 /pmc/articles/PMC4095654/ /pubmed/25089126 http://dx.doi.org/10.1155/2014/452737 Text en Copyright © 2014 A. M. Hinson et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Hinson, A. M.
Smith, C. W.
Siegel, E. R.
Stack, B. C.
Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary
title Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary
title_full Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary
title_fullStr Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary
title_full_unstemmed Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary
title_short Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection? A Histological and Microbiological Ten-Year Summary
title_sort is bisphosphonate-related osteonecrosis of the jaw an infection? a histological and microbiological ten-year summary
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095654/
https://www.ncbi.nlm.nih.gov/pubmed/25089126
http://dx.doi.org/10.1155/2014/452737
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