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Resistance of Cancer Cells to Targeted Therapies Through the Activation of Compensating Signaling Loops
The emergence of low molecular weight kinase inhibitors as “targeted” drugs has led to remarkable advances in the treatment of cancer patients. The clinical benefits of these tumor therapies, however, vary widely in patient populations and with duration of treatment. Intrinsic and acquired resistanc...
Autores principales: | von Manstein, Viktoria, Yang, Chul Min, Richter, Diane, Delis, Natalia, Vafaizadeh, Vida, Groner, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095943/ https://www.ncbi.nlm.nih.gov/pubmed/25045345 http://dx.doi.org/10.2174/1574362409666140206221931 |
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