Rapid Access to Spirocyclized Indolenines via Palladium-Catalyzed Cascade Reactions of Tryptamine Derivatives and Propargyl Carbonate

[Image: see text] We report the intermolecular palladium-catalyzed reaction of tert-butyl propargyl carbonate with tryptamine derivatives or other indole-containing bis-nucleophiles. The reaction proceeds under mild conditions and with low catalyst loadings to afford novel spiroindolenine products i...

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Detalles Bibliográficos
Autores principales: Montgomery, Thomas D., Nibbs, Antoinette E., Zhu, Ye, Rawal, Viresh H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096211/
https://www.ncbi.nlm.nih.gov/pubmed/24964382
http://dx.doi.org/10.1021/ol501409a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096211/
https://www.ncbi.nlm.nih.gov/pubmed/24964382
http://dx.doi.org/10.1021/ol501409a

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