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Rapid Access to Spirocyclized Indolenines via Palladium-Catalyzed Cascade Reactions of Tryptamine Derivatives and Propargyl Carbonate
[Image: see text] We report the intermolecular palladium-catalyzed reaction of tert-butyl propargyl carbonate with tryptamine derivatives or other indole-containing bis-nucleophiles. The reaction proceeds under mild conditions and with low catalyst loadings to afford novel spiroindolenine products i...
Autores principales: | Montgomery, Thomas D., Nibbs, Antoinette E., Zhu, Ye, Rawal, Viresh H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096211/ https://www.ncbi.nlm.nih.gov/pubmed/24964382 http://dx.doi.org/10.1021/ol501409a |
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