Cargando…

Undecaprenyl Diphosphate Synthase Inhibitors: Antibacterial Drug Leads

[Image: see text] There is a significant need for new antibiotics due to the rise in drug resistance. Drugs such as methicillin and vancomycin target bacterial cell wall biosynthesis, but methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) have now arisen an...

Descripción completa

Detalles Bibliográficos
Autores principales: Sinko, William, Wang, Yang, Zhu, Wei, Zhang, Yonghui, Feixas, Ferran, Cox, Courtney L., Mitchell, Douglas A., Oldfield, Eric, McCammon, J. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096218/
https://www.ncbi.nlm.nih.gov/pubmed/24827744
http://dx.doi.org/10.1021/jm5004649