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PEG–Polypeptide Block Copolymers as pH-Responsive Endosome-Solubilizing Drug Nanocarriers

[Image: see text] Herein we report the potential of click chemistry-modified polypeptide-based block copolymers for the facile fabrication of pH-sensitive nanoscale drug delivery systems. PEG–polypeptide copolymers with pendant amine chains were synthesized by combining N-carboxyanhydride-based ring...

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Detalles Bibliográficos
Autores principales:	Quadir, Mohiuddin A., Morton, Stephen W., Deng, Zhou J., Shopsowitz, Kevin E., Murphy, Ryan P., Epps, Thomas H., Hammond, Paula T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096223/ https://www.ncbi.nlm.nih.gov/pubmed/24813025 http://dx.doi.org/10.1021/mp500162w

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