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Multilayer Spheroids To Quantify Drug Uptake and Diffusion in 3D
[Image: see text] There is a need for new quantitative in vitro models of drug uptake and diffusion to help assess drug toxicity/efficacy as well as new more predictive models for drug discovery. We report a three-dimensional (3D) multilayer spheroid model and a new algorithm to quantitatively study...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical
Society
2014
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096226/ https://www.ncbi.nlm.nih.gov/pubmed/24641346 http://dx.doi.org/10.1021/mp500002y |