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Hydrogel-Based 3D Model of Patient-Derived Prostate Xenograft Tumors Suitable for Drug Screening

[Image: see text] The lack of effective therapies for bone metastatic prostate cancer (PCa) underscores the need for accurate models of the disease to enable the discovery of new therapeutic targets and to test drug sensitivities of individual tumors. To this end, the patient-derived xenograft (PDX)...

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Detalles Bibliográficos
Autores principales: Fong, Eliza L. S., Martinez, Mariane, Yang, Jun, Mikos, Antonios G., Navone, Nora M., Harrington, Daniel A., Farach-Carson, Mary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096229/
https://www.ncbi.nlm.nih.gov/pubmed/24779589
http://dx.doi.org/10.1021/mp500085p