PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G(+) -Toxins

Gram positive (G(+)) infections make up ∼50% of all acute lung injury cases which are characterized by extensive permeability edema secondary to disruption of endothelial cell (EC) barrier integrity. A primary cause of increased permeability are cholesterol-dependent cytolysins (CDCs) of G(+)-bacter...

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Detalles Bibliográficos
Autores principales: Chen, Feng, Kumar, Sanjiv, Yu, Yanfang, Aggarwal, Saurabh, Gross, Christine, Wang, Yusi, Chakraborty, Trinad, Verin, Alexander D., Catravas, John D., Lucas, Rudolf, Black, Stephen M., Fulton, David J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096401/
https://www.ncbi.nlm.nih.gov/pubmed/25020117
http://dx.doi.org/10.1371/journal.pone.0099823

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