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A case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton species
BACKGROUND: Fungal keratitis is difficult to treat that can result in corneal blindness requiring penetrating keratoplasty and in fungal endothalmitis. We report a case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton. CASE PRESENTATION: A 77-year old male presented with...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096410/ https://www.ncbi.nlm.nih.gov/pubmed/25015110 http://dx.doi.org/10.1186/1471-2415-14-90 |
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author | Jin, Ki Won Jeon, Hyun Sun Hyon, Joon Young Wee, Won Rynag Suh, Wool Shin, Young Joo |
author_facet | Jin, Ki Won Jeon, Hyun Sun Hyon, Joon Young Wee, Won Rynag Suh, Wool Shin, Young Joo |
author_sort | Jin, Ki Won |
collection | PubMed |
description | BACKGROUND: Fungal keratitis is difficult to treat that can result in corneal blindness requiring penetrating keratoplasty and in fungal endothalmitis. We report a case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton. CASE PRESENTATION: A 77-year old male presented with ocular pain, conjunctival injection, and severe loss of vision in his left eye. His best corrected visual acuity was hand movements in the left eye, and slit-lamp examination showed a corneal ulcer with feathery margin and hypopyon. Bacterial and fungal smear/culture showed no organism, and there was no improvement in spite of treatment with topical fortified 5% cefazolin and 2% tobramycin. Trichophyton species was identified by repeated cultures. We found onychomycosis on the patient’s foot, where the same fungal species were identified. Regimen was changed to topical itraconazole and systemic intravenous itraconazole. No clinical improvement was observed, so therapeutic penetrating keratoplasty and cryotherapy was done with continuation of antifungal therapy. The graft was clear at postoperative 1 month and no evidence of recurrence was found. CONCLUSION: It is important to identify the pathogen of keratitis because early identification of pathogen causing keratitis provides the appropriate treatment in early phase of keratitis. It is necessary to search for other fungal skin infections such as onychomycosis and athelete’s foot considering the fungal keratitis following skin infection. In addition, fungal skin infection including onychomycosis should be treated for prevention of fungal keratitis as soon as possible. |
format | Online Article Text |
id | pubmed-4096410 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40964102014-07-15 A case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton species Jin, Ki Won Jeon, Hyun Sun Hyon, Joon Young Wee, Won Rynag Suh, Wool Shin, Young Joo BMC Ophthalmol Case Report BACKGROUND: Fungal keratitis is difficult to treat that can result in corneal blindness requiring penetrating keratoplasty and in fungal endothalmitis. We report a case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton. CASE PRESENTATION: A 77-year old male presented with ocular pain, conjunctival injection, and severe loss of vision in his left eye. His best corrected visual acuity was hand movements in the left eye, and slit-lamp examination showed a corneal ulcer with feathery margin and hypopyon. Bacterial and fungal smear/culture showed no organism, and there was no improvement in spite of treatment with topical fortified 5% cefazolin and 2% tobramycin. Trichophyton species was identified by repeated cultures. We found onychomycosis on the patient’s foot, where the same fungal species were identified. Regimen was changed to topical itraconazole and systemic intravenous itraconazole. No clinical improvement was observed, so therapeutic penetrating keratoplasty and cryotherapy was done with continuation of antifungal therapy. The graft was clear at postoperative 1 month and no evidence of recurrence was found. CONCLUSION: It is important to identify the pathogen of keratitis because early identification of pathogen causing keratitis provides the appropriate treatment in early phase of keratitis. It is necessary to search for other fungal skin infections such as onychomycosis and athelete’s foot considering the fungal keratitis following skin infection. In addition, fungal skin infection including onychomycosis should be treated for prevention of fungal keratitis as soon as possible. BioMed Central 2014-07-11 /pmc/articles/PMC4096410/ /pubmed/25015110 http://dx.doi.org/10.1186/1471-2415-14-90 Text en Copyright © 2014 Jin et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Jin, Ki Won Jeon, Hyun Sun Hyon, Joon Young Wee, Won Rynag Suh, Wool Shin, Young Joo A case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton species |
title | A case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton species |
title_full | A case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton species |
title_fullStr | A case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton species |
title_full_unstemmed | A case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton species |
title_short | A case of fungal keratitis and onychomycosis simultaneously infected by Trichophyton species |
title_sort | case of fungal keratitis and onychomycosis simultaneously infected by trichophyton species |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096410/ https://www.ncbi.nlm.nih.gov/pubmed/25015110 http://dx.doi.org/10.1186/1471-2415-14-90 |
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