The basic amino acids in the coiled-coil domain of CIN85 regulate its interaction with c-Cbl and phosphatidic acid during epidermal growth factor receptor (EGFR) endocytosis

BACKGROUND: During EGFR internalization CIN85 bridges EGFR-Cbl complex, endocytic machinery and fusible membrane through the interactions of CIN85 with c-Cbl, endophilins and phosphatidic acid. These protein-protein and protein-lipid interactions are mediated or regulated by the positively charged C...

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Detalles Bibliográficos
Autores principales: Zheng, Xiudan, Zhang, Jing, Liao, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096430/
https://www.ncbi.nlm.nih.gov/pubmed/25005938
http://dx.doi.org/10.1186/1471-2091-15-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096430/
https://www.ncbi.nlm.nih.gov/pubmed/25005938
http://dx.doi.org/10.1186/1471-2091-15-13

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